C-46 | In-Hospital Mortality in Patients With Pulmonary Embolism Managed With Ultrasound-Assisted Catheter-Directed Thrombolysis Compared to Systemic Thrombolysis

Patients with high-risk or intermediate-risk pulmonary embolism (PE) require more aggressive therapy, such as systemic thrombolysis. Although parenteral thrombolysis leads to faster clot resolution, it is associated a high risk for significant bleeding and its complications. The use of catheter-directed (CDT) decreases exposure thrombolytics reduces the complications mortality. Adding ultrasound CDT can potentially decrease dosing local make even safer patients. This retrospective cohort study identified 1,007 patients diagnosed across several facilities. were stratified into two groups based on treatment they received, group that received (ST), 432 (42.9 %), ultrasound-assisted (EKOS), 575 (57.1 %). aim was explore immediate mortality from direct indirect arising PE management in treated vs. EKOS. We used logistic regression analyze data. who managed ST likely expire than those EKOS (OR 2.893, CI 1.766∼5.041, p<0.001). passed experience tachycardia 2.432, 1,299∼4.556, p<0.001) vasopressors 13.331, 8.075∼22.006, There 70 (6.95 %) deaths 26 (2.58 group. are die illustrates better outcomes using PE. However, limitation this small sample possible cofounders, which warrants future studies.